Sylvester is sleeping on the ledge of a tall building. After observing mild-mannered Dr. Jekyll drinking a Mr. Hyde potion, and briefly turning into a monstrous alter ego, Sylvester laughs it off and resumes his sleep. In a dream-like sequence, Sylvester chases some pigeons away after their coos disrupt his nap. He then pursues his prey, Tweety, along the building's ledge. Tweety escapes inside and hides in the Hyde formula. Sylvester demands that Tweety show himself, which he does: he's turned into an ugly, giant bird of prey that - after years of harassment and being chased and with payback on his mind - begins chasing Sylvester!
Sylvester is frantically trying to get the elevator to come up, and he turns and looks down the corner, and Tweety Hyde is ambling along, laughing maniacally. For most of the rest of the cartoon, Tweety frequently switches between his usual, innocent self, which Sylvester chases, and the evil bird-monster, which goes after the cat. After several back-and-forth chases, Sylvester nabs a normal-sized Tweety. Failing to realize the monster bird and his potential meal are one and the same, the cat locks himself in a small kitchen, throws the key out the window and begins to "make that Tweety sandwich I've been dreaming of." But while Sylvester is searching for some ketchup, Tweety changes back into his Hyde-like self and devours his adversary whole. Sylvester frees himself and tries to escape the room as his hunter murderously stalks him down.
Just then, Sylvester awakens to realize that this whole experience was a dream and he sees a normal-sized Tweety struggling to fly to the ledge of the building. Sylvester is convinced that Tweety poses a giant risk to his well-being and runs through a wall to escape! Two cats observe his action and refer to it as cowardice. Tweety agrees.
On ABC's The Bugs Bunny and Tweety Show, the scene of Sylvester, who is trying to escape the Hyde-esque Tweety Bird, looking down, getting on the ledge, telling Tweety, "I'll jump," then asiding to the audience, "I've got a choice?" was re-edited to remove the line, "I'll jump! I've got a choice?" as the censors felt it had suicidal implications, and replaced the removed line with the POV shot of Sylvester looking down and seeing just how far he has to jump to get away from the monstrous Tweety. Surprisingly, this wasn't edited when Cartoon Network and Boomerang aired this short, despite temporarily airing a version of "For Scent-imental Reasons" that had a window-jumping scene and dialogue that was censored because it seemingly advocated suicide.
- This cartoon was used in the movie Daffy Duck's Quackbusters with new animation showing Sylvester in Daffy's office.
- It was also used in Bugs Bunny's Howl-oween Special.
- This cartoon lacks a MPAA number on the credits card.
- This is one of the few, if not only, times in which Tweety chases Sylvester.
- The Sylvester & Tweety Mysteries episode called "London Broiled" is based on this cartoon, which also has Tweety turning into a Hyde-like monster.
- The two cats in the end of the cartoon reappear in "London Broiled", as well as making cameos in the series from time to time.
- Michael Maltese wrote this cartoon, but was not credited in this cartoon as he had left the Warner Bros. studio for Hanna-Barbera before its release.
- "Voice Characterizations" is replaced with "Voices" in the opening credits.
- On Cartoon Network and Boomerang, this cartoon is shown with PAL audio.
- The restored HBO Max print of this cartoon incorrectly uses the "A VITAPHONE RELEASE" byline from another cartoon (most likely from "From Hare to Heir") and scraps the original 1959-60 end card.
TV Title Cards
|1942||A Tale of Two Kitties|
|1944||Birdy and the Beast|
|1945||A Gruesome Twosome|
|1948||I Taw a Putty Tat|
|1949||Bad Ol' Putty Tat|
|1950||Home, Tweet Home • All a Bir-r-r-d • Canary Row|
|1951||Putty Tat Trouble • Room and Bird • Tweety's S.O.S. • Tweet Tweet Tweety|
|1952||Gift Wrapped • Ain't She Tweet • A Bird in a Guilty Cage|
|1953||Snow Business • Fowl Weather • Tom Tom Tomcat • A Street Cat Named Sylvester • Catty Cornered|
|1954||Dog Pounded • Muzzle Tough • Satan's Waitin'|
|1955||Sandy Claws • Tweety's Circus • Red Riding Hoodwinked • Heir-Conditioned|
|1956||Tweet and Sour • Tree Cornered Tweety • Tugboat Granny|
|1957||Tweet Zoo • Tweety and the Beanstalk • Birds Anonymous • Greedy for Tweety|
|1958||A Pizza Tweety-Pie • A Bird in a Bonnet|
|1959||Trick or Tweet • Tweet and Lovely • Tweet Dreams|
|1960||Hyde and Go Tweet • Trip for Tat|
|1961||The Rebel Without Claws • The Last Hungry Cat|
|1962||The Jet Cage|
|1964||Hawaiian Aye Aye|
|2011||I Tawt I Taw a Puddy Tat|