Spike the Bulldog and Chester the Terrier are animated cartoon characters in the Warner Bros. Looney Tunes and Merrie Melodies series of cartoons. Spike is a burly, gray bulldog who wears a red sweater, a brown bowler hat, and a perpetual scowl. Chester is the exact opposite, a small and jumpy Jack Russell terrier with yellow fur and brown, perky ears.
The characters starred in only two shorts, both directed by animator Friz Freleng and having the same concept. Each of these two cartoons have a repeated formula: Chester, who idolizes Spike for being "big and strong" in comparison to him whom is "so puny", constantly fawns over Spike and follows everywhere he goes much to the latter's annoyance, and Spike turns down all of Chester's ideas of fun except for beating up a cat who turns out to be none other than Sylvester. As soon as Spike and Chester chase Sylvester, Spike runs afoul into aggressive feline "monsters" who prove to be far more dangerous than Spike himself, which ultimately results Spike getting pummeled heavily by the "monsters" which Chester remains oblivious to, and when Spike cowers in fear from the beatings he received, Chester fails to understand what Spike has gone through and just bluntly dismisses Spike as a coward.
The first of these cartoon films was 1952's "Tree for Two". In it, Chester tells his idol Spike that he knows of a cat that they can beat up. The cat is Freleng's own Sylvester, but every time Spike thinks he has the cat cornered, a runaway zoo black panther appears in Sylvester's place, thrashing the dog instead. When Chester decides to have a go of it, however, Sylvester finds himself at the little dog's mercy. By the cartoon's end, Spike and Chester have switched roles; Spike is the fawning sycophant, and Chester the smug prizefighter.
The characters' second outing came in the 1954 film "Dr. Jerkyl's Hide". Spike (here called "Alfie" and having a different accent) is once again after Sylvester, only this time it is Sylvester himself who pummels the poor pooch, thanks to a potion that transforms him into a feline monster. Chester, of course, never sees this transformed Sylvester, thinking his buddy is being beaten by the tiny tomcat. The final loss of face for Alfie is his being thrashed by a fly that has also been affected by the potion, as it occurs in front of Chester's eyes. Like the previous cartoon, Spike and Chester have switched roles at the end; Spike is the fawning sycophant, and Chester the smug prizefighter.
In 1988, a live-action version of the two dogs appeared in a commercial for Kibbles 'n Bits, portrayed by both a real bulldog and terrier respectively. 
They also had a cameo in Space Jam as doctors taking in a flattened Stan Podolak to the hospital. They also have a cameo in Looney Tunes Back in Action playing poker with Charlie Dog, Ham and Ex, Barnyard Dawg and the Russian Dog at the casino.
They also appeared in Sega 1993 video game Sylvester and Tweety in Cagey Capers in the fourth level as silhouettes in the window.
Spike made a brief silent cameo without Chester in The Looney Tunes Show's Merrie Melody "Blow My Stack" during the Anger Management sequence run by Clarence Cat alongside his arch-nemesis Sylvester as well as other Looney Tunes antagonists such as Yosemite Sam, Elmer Fudd, The Crusher, Wile E. Coyote and Shropshire Slasher.
- Stan Freberg (1952-1996)
- Frank Welker (2003)
- Another similar-looking bulldog character which Friz Freleng also created appeared in other cartoons with Sylvester and Tweety, but this character is not Spike; he is officially known as Hector the Bulldog. Several Tom and Jerry cartoons produced by MGM also featured a character named Spike the Bulldog (and his son, Tyke). This is another character, unrelated to the Spike used by Freleng.