While chasing Road Runner, Wile E. Coyote is hit with a briefcase thrown from a crook's car in a police chase. The briefcase is actually a spy kit containing gadgets that Wile E. tries to use on Road Runner, but which all fail as usual, including:
Sleeping gas: Road Runner dodges the gas and blows it back at Wile E., who sleepwalks off a cliff. The Road Runner places the alarm clock right beside the hole at the bottom of the gorge. Wile E. simply puts a hand out to shut it off.
Do-it-yourself time bomb that Wile E. mails to Road Runner, but is returned to the Coyote by Road Runner disguised as a mailman for insufficient postage. As Wile E. takes the package back into his cave for an extra stamp, BOOM!
Explosive putty which is applied under a huge bolder with a mound of bird seed placed nearby. Wile E. hides behind another boulder farther away and lights the fuse, only to be crushed by the flying boulder.
Spy car equipped with machine guns, ejection seat and cannon: The bullets from the machine guns ricochet off a bolder and blow away the car top, the Coyote ejects himself from the car while suspended upside down, and the force from the cannon sends the car backwards, running over the Coyote who then tries to dodge the cannonball.
Remote control flying bombs: Wile E. tests the first bomb on a cactus, then sets the remote control for the next bomb to follow Road Runner, who hides under the Coyote's stool and escapes in time for Wile E. to take the explosion. When the smoke clears, the dazed Coyote has the bomb's wings attached to his arms, prompting Road Runner to set the remote control for the moon.
- This is the final appearance of Road Runner and Wile E. Coyote in the Golden Age of American Animation.
- It is the second of two Wile E. Coyote and Road Runner shorts directed by Robert McKimson, the first being "Rushing Roulette".
- This is also the first and only Road Runner and Wile E. Coyote cartoon to feature music by Walter Greene. It is the first to feature an all-original score since "Run, Run, Sweet Road Runner" as the other shorts subcontracted to Format Films used stock music cues due to low budgets.
- This is the second of three DePatie-Freleng Looney Tunes and Merrie Melodies shorts to use a few Hanna-Barbera sound effects, the other two being "Clippety Clobbered" and "Daffy's Diner".
- This is the last Looney Tunes or Merrie Melodies short to rely on reusing footage from previous shorts of both series.